Currently Funded

  • Kazuma Nakagawa
    Kazuma Nakagawa, MD

    Principal Investigator, CNPHDR Research Study: “Evaluation of Stroke Disparities in Native Hawaiians and other Pacific Islanders"

    Associate Professor of Medicine, University of Hawai‘i, John A. Burns School of Medicine

    Director of Stroke Center and Medical Director of Obstetric Neurovascular Service, The Queen’s Medical Center, Honolulu, HI


    Interests:  

    My two research interests are "Racial disparities in stroke risk factors and outcomes among the Native Hawaiians and other Pacific Islanders who are living in Hawai‘i" and "Characterization and application of cerebral autoregulation measurements using transcranial Doppler ultrasound in patients with intracerebral hemorrhage".

    Honors: 

    1996:  Furman Scholar Award

    1999:  Howard Hughes Undergraduate Research Fellowship

    2004:  Alpha Omega Alpha Honor, University of Florida College of Medicine

    2008:  Young Investigator Award, Neurocritical Care Society

    2009:  Founders Award, American Academy of Neurology

    2011:  Health Initiative Scholar, University of Hawai‘i RMATRIX

    2012:  Loan Repayment Program, NIH/NIMHD

    Selected Publications: 

    1. Nakagawa K, Sheikh SI, Snuderl M, Frosch MP, Greenberg SM. A new Thr49Pro transthyretin gene mutation associated with leptomeningeal amyloidosis. J Neurol Sci. 2008 Sep 15;272(1-2):186-90. doi: 10.1016/j.jns.2008.05.014. Epub 2008 Jun 24. PMID: 18579156

    2. Nakagawa K, Sorond FA, Ropper AH. Ultra-early magnetic resonance imaging findings of eclampsia. Arch Neurol. 2008 Jul;65(7):974-6. doi: 10.1001/archneur.65.7.974. PMID: 18625869

    3. Nakagawa K, Serrador JM, LaRose SL, Moslehi F, Lipsitz LA, Sorond FA. Autoregulation in the posterior circulation is altered by the metabolic state of the visual cortex. Stroke. 2009 Jun;40(6):2062-7. doi: 10.1161/STROKEAHA.108.545285. Epub 2009 Apr 9. PMID: 19359628

    4. Nakagawa K, Bianchi MT, Nakagawa SS, Sorond FA. Aggressive care after a massive stroke in young patients: Is that what they want? Neurocrit Care. 2010 Aug;13(1):118-22. doi: 10.1007/s12028-010-9340-7. PMID: 20182921

    5. Dhand A, Nakagawa K, Nagpal, S, Gelfand JM, Kim AS, Smith WS, Tihan T. Cardiac rupture after intravenous t-PA administration in acute ischemic stroke. Neurocrit Care. 2010 Oct;13(2):261-2. doi: 10.1007/s12028-010-9384-8. PMID: 20697837

    6. Nakagawa K, Hills NK, Kamel H, Morabito, Diane, Patel PV, Manley GT, Hemphill JC 3rd. The effect of decompressive hemicraniectomy on brain temperature after severe brain injury. Neurocrit Care. 2011 Aug;15(1):101-6. doi: 10.1007/s12028-010-9446-y. PMID: 21061187

    7. Deegan BM, Serrador JM, Nakagawa K, Jones E, Sorond FA, Olaighin G. The effect of blood pressure calibrations and transcranial Doppler signal loss on transfer function estimates of cerebral autoregulation. Med Eng Phys. 2011 Jun;33(5):553-62. doi: 10.1016/j.medengphy.2010.12.007. Epub 2011 Jan 15. PMID: 21239208

    8. Kamel H, Navi B, Nakagawa K, Hemphill JC, Ko NU. Hypertonic saline versus mannitol for the treatment of elevated intracranial pressure: A meta-analysis of randomized clinical trials. Crit Care Med. 2011 Mar;39(3):554-9. doi: 10.1097/CCM.0b013e318206b9be. PMID: 21242790

    9. Nakagawa K, Tang JF. Physiologic response of human brain death and the use of vasopressin for successful organ transplantation. J Clin Anesth. 2011 Mar;23(2):145-8. doi: 10.1016/j.jclinane.2009.12.015. PMID: 21377081

    10. Nakagawa K, Smith WS. Paradoxical vasoconstrictive effect in the contralateral hemisphere after carotid stenting. Neurology. 2011 Jul 19;77(3):300. doi: 10.1212/WNL.0b013e318225ab1d. No abstract available. PMID: 21768600

    11. Nakagawa K, Serrador JM, LaRose SL, Sorond FA. Dynamic cerebral autoregulation after intracerebral hemorrhage: A case-control study. BMC Neurol. 2011 Aug 31;11:108. doi: 10.1186/1471-2377-11-108. PMID: 21884574

    12. Navi BB, Kamel H, McCulloch CE, Nakagawa K, Naravetla B, Moheet AM, Wong C, Johnston SC, Hemphill JC 3rd, Smith WS. Accuracy of neurovascular fellows’ prognostication of outcome after subarachnoid hemorrhage. Stroke. 2012 Mar;43(3):702-7. doi: 10.1161/STROKEAHA.111.639161. Epub 2012 Jan 5. PMID: 22223238

    13. Navi BB, Kamel H, McCulloch CE, Nakagawa K, Naravetla B, Moheet AM, Wong C, Johnston SC, Hemphill JC 3rd, Smith WS. Accuracy of neurovascular fellows’ prognostication of outcome after subarachnoid hemorrhage. Stroke. 2012 Mar;43(3):702-7. doi: 10.1161/STROKEAHA.111.639161. Epub 2012 Jan 5. PMID: 22223238

    14. Nakagawa K, Chang CW, Koenig MA, Yu M, Tokumaru S. Treatment of refractory intracranial hypertension with 23.4% saline in children with severe traumatic brain injury. J Clin Anesth. 2012 Jun;24(4):318-23. doi: 10.1016/j.jclinane.2011.10.011. PMID: 22608588

    15. Nakagawa K, Smith WS. Evaluation and management of increased intracranial pressure. Continuum (Minneap Minn). 2011 Oct;17(5 Neurologic Consultation in the Hospital):1077-93. doi: 10.1212/01.CON.0000407061.25284.28. PMID: 22809983

    16. Nakagawa K, Koenig MA, Seto TB, Asai SM, Chang CW. Racial disparities among Native Hawaiians and Pacific Islanders with intracerebral hemorrhage. Neurology. 2012 Aug 14;79(7):675-80. doi: 10.1212/WNL.0b013e3182608c6f. Epub 2012 Jul 18. PMID: 22815551

    17. Nakagawa K, Koenig MA, Asai SM, Chang CW, Seto TB. Disparities among Asians and Native Hawaiians and Pacific Islanders with ischemic stroke. Neurology. 2013 Feb 26;80(9):839-43. doi: 10.1212/WNL.0b013e3182840797. Epub 2013 Jan 30. PMID: 23365055

    18. Nakagawa K, Hoshide RR, Asai SM, Johnson KG, Beniga JG, Albano MC, del Castillo JL, Chang CW, Koenig MA. Favorable outcomes for Native Hawaiians and other Pacific Islanders with severe traumatic brain injury. Hawaii J Med Public Health. 2013 Apr;72(4):129-35. PMID: 23795313

    19. Nakagawa K, Vento MA, Seto TB, Koenig MA, Asai SM, Chang CW, Hemphill JC 3rd. Sex differences in the use of early do-not-resuscitate orders after intracerebral hemorrhage. Stroke. 2013 Nov;44(11):3229-31. doi: 10.1161/STROKEAHA.113.002814. Epub 2013 Aug 27. PMID: 23982712

    20. Koenig MA, Holt JL, Ernst T, Buchthal SD, Nakagawa K, Stenger VA, Chang L. MRI default mode network connectivity is associated with functional outcome after cardiopulmonary arrest. Neurocrit Care. 2014 Jun;20(3):348-57. doi: 10.1007/s12028-014-9953-3. PMID: 24464830

    21. Nakagawa K, Lee SB. Predominant intraventricular hemorrhage from a ruptured posterior communicating artery aneurysm. Neurohospitalist. 2014 Jul;4(3):164. doi: 10.1177/1941874413507929. No abstract available. PMID: 24982722

    22. Nakagawa K, Obana KK. Willingness to favor aggressive care and live with disability following severe traumatic brain injury: a survey of healthy young adults in Hawai'i. Hawaii J Med Public Health. 2014 Jul;73(7):212-6. PMID: 25089232

    23. Ing MM, Vento MA, Nakagawa K, Linton KF. A qualitative study of transportation challenges among intracerebral hemorrhage survivors and their caregivers. Hawaii J Med Public Health. 2014 Nov;73(11):353-7. PMID: 25414805

    24. Nakagawa K, Vento MA, Ing MM, Asai SM. Impact of Diabetes on Prolonged Hospital Stay among Native Hawaiians and other Pacific Islanders with Ischemic Stroke. Hawaii J Med Public Health. 2014 Dec;73(12 Suppl 3):4-7. PMID: 25535594

    25. Nakagawa K, Galati A, Juarez DT. The excess cost of interisland transfer of intracerebral hemorrhage patients. Am J Emerg Med. 2015 Jan 9. pii: S0735-6757(15)00002-9. doi: 10.1016/j.ajem.2015.01.001. [Epub ahead of print] PMID: 25624077

    26. Nakagawa K, Vento MA, Ing MM, Seto TB. Racial disparities in methamphetamine-associated intracerebral hemorrhage. Neurology. 2015 Feb 6. pii: 10.1212/WNL.0000000000001339. [Epub ahead of print] PMID: 25663228

    PubMed Publications Listing:  Nakagawa Kazuma